Keybiotech Human Factor V Leiden Real Time PCR Detection Kit

Cat# KBHFV01

Overview:

Factor V Leiden (FVL), an inherited thrombophilia, is the most common genetic risk factor for venous thrombosis. The FVL mutation is a G>A single nucleotide polymorphism (SNP) in the Factor V gene resulting in an arginine to glutamine (R506Q) amino acid change. This causes the protein to resist degradation, which disrupts the natural anticoagulant system.

Product Details:

This kit is an in vitro real-time PCR test for the qualitative detection of the Factor V Leiden G1691A mutation in human whole blood samples. It is based on allele specific PCR with hydrolysis probe detection and is a highly sensitive qPCR kit.

The Keybiotech Human Factor V Leiden qPCR kit is sensitive down 200 copies per 25uL reaction under our validation methods and devices. The Keybiotech Human Factor V Leiden qPCR kit is up to 100% specific for the Human Factor V Leiden G1691A mutation under our validation methods and devices.